Temperature-Controlled Microchip Liquid Chromatography System
نویسندگان
چکیده
Temperature-Controlled Microchip Liquid Chromatography System Thesis by Victor Chi-Yuan Shih Doctor of Philosophy in Electrical Engineering California Institute of Technology High-performance liquid chromatography (HPLC) is one of the most important analytical tools heavily used in the fields of chemistry, biotechnology, pharmaceutics, and the food industry. The power of liquid chromatography comes from its ability to achieve molecular separation with extremely high efficiency and its great flexibility of incorporating versatile sensors for detecting a broad range of analytes. In the past decades, great efforts have been put into liquid chromatography instrumentation and methods, aiming to further improve separation efficiency, sensitivity, repeatability, throughput, and costs. The contribution of this thesis is to illustrate with real examples the great potential of MEMS microchip liquid chromatography systems with on-chip temperature control for replacing and improving the conventional desktop HPLC
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